Neuregulin1/ErbB4-induced migration in ST14A striatal progenitors: calcium-dependent mechanisms and modulation by NMDA receptor activation
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چکیده
منابع مشابه
Glutamate promotes proliferation of striatal neuronal progenitors by an NMDA receptor-mediated mechanism.
Increasing evidence suggests that classical neurotransmitters play important roles in the development of the mammalian CNS. We used in vivo and in vitro models to identify a novel role for glutamate in striatal neurogenesis mediated by NMDA receptors. In utero exposure to NMDA receptor antagonists during striatal neurogenesis caused a dramatic reduction in the total number of adult striatal neu...
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The effect of NMDA (N-methyl-D-aspartate) receptor antagonists on tolerance to morphine antinociception was investigated in mice. Daily subcutaneous administration of 50 mg/kg of morphine hydrochloride for three days induced tolerance to different (3,6 and 9 mg/kg) test doses of morphine. The tolerance obtained was decreased by pretreatment of animals with single or repeated doses of compe...
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Afferent stimulation of pyramidal cells in the basolateral amygdala produced mixed excitatory postsynaptic potentials (EPSPs) mediated by N-methyl-D-aspartate (NMDA) and non-NMDA glutamate receptors during whole cell current-clamp recordings. In the presence of GABA(A) receptor blockade, the mixed EPSPs recruited a large "all-or-none" depolarizing event. This recruited event was voltage depende...
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접수일:2009년 10월 15일, 1차 수정일:2009년 10월 30일 승인일:2009년 11월 27일 책임저자:김두식, (602-072) 부산시 서구 암남동 34 고신의료원 마취통증의학과 Tel: 051-990-6283, Fax: 051-254-2504 E-mail: [email protected] 본 연구는 2009년도 고신대학교 의과대학 학술연구비의 지원에 의해 수행되었음. Received October 15, 2009, Revised October 30, 2009 Accepted November 27, 2009 Correspondence to: Doo Sik Kim Department of Anesthesiology and Pain Medicine, Kosin University C...
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In countries infected with HIV clade B, some patients develop a rapidly progressive dementia that if untreated results in death. In regions of the world infected with HIV clade C, only milder forms of cognitive impairment have been recognized. HIV-infected macrophages are the principal mediators of dementia. HIV clade C, however, efficiently infects macrophages and HIV-infected macrophages are ...
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ژورنال
عنوان ژورنال: BMC Neuroscience
سال: 2011
ISSN: 1471-2202
DOI: 10.1186/1471-2202-12-103